| Customization: | Available |
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| Varieties: | General Disease Prevention Medicine |
| Component: | Chemical Synthetic Drugs |
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This product is produced in strict accordance with GMP organization and in line with quality standards
| Product name | Ampicillin |
| Physical and Chemical Properties | This product is a semi synthetic animal specific hydrolysate of Tylosin. Seed is a white or almost white powder that is easily soluble in methanol, acetonitrile, or acetone, but insoluble in water. Its phosphate or tartrate salts are commonly used in beds. |
| Function and Use | This product is a semi synthetic broad-spectrum antibiotic that has similar or slightly weaker effects on Gram positive bacteria than penicillin. It has similar or slightly stronger effects on most Gram negative bacteria such as Escherichia coli, Salmonella, Proteus, Pasteurella, and Hemophilus parahaemolyticus than chloramphenicol, but not on kanamycin, gentamicin, and polymyxin. It still has a strong effect on chloramphenicol resistant bacteria, but is ineffective against Pseudomonas aeruginosa and resistant Staphylococcus aureus. This product is acid resistant and enzyme resistant, and can be easily absorbed by oral or intramuscular injection. It is mainly used for sepsis, respiratory, digestive, and urogenital infections caused by sensitive bacteria, such as pneumonia in young horses and calves, pleuropneumonia in pigs, white dysentery in calves, white dysentery in piglets, Pasteurella bovis disease, mastitis, chicken white dysentery, avian typhoid fever, feline infectious peritonitis, etc. This product has an enhanced therapeutic effect when combined with aminoglycoside antibiotics such as gentamicin. |
| Usage and Dosage | This product is acid resistant and can be taken orally. It can be absorbed by single stomach animals by 30% to 55%. Gastrointestinal contents can reduce bioavailability; Ruminant animals have poor absorption, with a bioavailability of only 2.1% for oral administration in sheep. This product is well absorbed by intramuscular injection, with a bioavailability of over 80%. After absorption, it can be widely distributed in various tissues, including liver, lungs, muscles, bile, ascites, pleural fluid, and joint fluid. The apparent distribution volume of dogs is 0.3L/kg, while that of cats is 0.167L/kg. After absorption, this product can enter cerebrospinal fluid. When meningitis occurs, its concentration can reach 10% to 60% of serum concentration, and the plasma protein binding rate is about 20%. It can pass through the placental barrier and has low milk content. After absorption, this product is mainly eliminated through renal tubules, and some of it is hydrolyzed into inactive penicillin thiazole and excreted in urine. The half-lives of intramuscular injection of this product in horses, water buffalo, yellow cattle, dairy goats, and pigs are 1.2-2.2 hours, 1.26 hours, 0.98 hours, 0.92 hours, and 0.57-1.06 hours, respectively. The half-life of dogs and cats is 45-80 minutes. Propofol can delay the excretion of this product, increase blood drug concentration, and prolong half-life. |
| Storage | Stored under shade and sealed |
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