| Customization: | Available |
|---|---|
| Varieties: | General Disease Prevention Medicine |
| Component: | Chemical Synthetic Drugs |
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| Product name | Iron Dextran Injection |
| Composition (per gram) |
Iron Dextran |
| Character | This product is a dark brown colloidal solution. |
| Indications | Antianemia drug. For iron deficiency anemia in foals, calves, piglets, puppies and fur-bearing animals. |
| Dosage and Administration | Intramuscular injection: one dose, foal and calf 2 ~ 6ml; Piglets 1 ~ 2ml; Puppies 0.2 ~ 2ml; Fox 0.5 ~ 2ml; Mink 0.3 ~ 1ml. |
| Cautions | (1) The toxicity of this product is relatively large, and the intramuscular injection dose should be strictly controlled. (2) intramuscular injection can cause local pain, should be deep intramuscular injection. (3) Injection of pigs over 4 weeks of age can cause pigmentation of buttock muscles. (4) Need to antifreeze, long-term precipitation can occur. (5) Iron salt can react with many chemicals or drugs, so it is not suitable to be taken internally with other drugs at the same time or in combination. |
| Adverse reactions | Piglets injected with iron will occasionally be unstable due to muscle weakness, which can lead to death in severe cases. |
| Storage | store away from light |
| Drug interaction |
Pharmacodynamics: Iron is the main component of hemoglobin and myoglobin. Hemoglobin is the main element of red blood cells Need oxygen carriers. Myoglobin is the part of muscle cells that store oxygen to help provide oxygen to muscles during exercise. With tricarboxylic acid,Most enzymes and factors associated with the ring contain iron or function only in the presence of iron. So positive for iron-deficient animals ,After iron supplementation, in addition to accelerated hemoglobin synthesis, symptoms associated with iron deficiency and decreased activity of iron-containing enzymes in the tissue such as growth slowness, abnormal behavior, and lack of physical strength can be gradually corrected. Pharmacokinetic : iron for injection, absorption is more rapid than oral; Blood drug for 24 to 48 hours after intramuscular injection of iron dextran When the concentration reaches the peak, the molecule is larger, absorbed by lymphatic vessels and then transferred into the blood, and the blood concentration increases slowly. Intravenously After intramuscular injection and absorption into the blood circulation, it is phagocytic and decomposed into iron and dextran by the mononuclear phagocytic cell system. Iron absorption ,It is then oxidized to ferric ions by ceruloplasmin in the blood, which then binds to transferrin receptors in the form of pinocytosis.It enters the cell and is used by hematopoietic cells. It can also be accumulated in the form of ferritin or hemosiderin in the liver, spleen, bone marrow and bone marrow ,Other mononuclear phagocyte systems. Protein binding rates are high in hemoglobin, myoglobin, enzymes, and eggs that transport iron .It is low in albumen and very low in ferritin or hemosiderin. |
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