| Customization: | Available |
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| Varieties: | General Disease Prevention Medicine |
| Component: | Chemical Synthetic Drugs |
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| Product Name | Gentamicin Sulfate Soluble Powder |
| Composition (per gram) |
Gentamicin Sulfate |
| Characteristics | This product is white or white powder |
| Drug Interaction | Gentamicin sulfate is a broad-spectrum antibiotic. Gentamicin sulfate can be used in poultry, aquaculture, livestock and other animals, mainly for the treatment of bacterial and mycoplasma diseases. |
| Pharmacological Action | Pharmacodynamics:Gentamicin sulfate is an antibiotic with bactericidal action, killing bacteria by binding to the 30S subunit of ribosomes and disrupting protein synthesis. This disrupts bacterial function and leads to cell death. Effective against various Gram-negative and some Gram-positive bacteria, gentamicin is reserved for serious infections. However, it requires careful monitoring due to potential adverse effects like nephrotoxicity and ototoxicity. The drug's concentration-dependent killing, post-antibiotic effect, and need for individualized dosing contribute to its pharmacological profile. Pharmacokinetics:Gentamicin sulfate is administered parenterally due to limited oral absorption. It quickly reaches peak concentrations after intramuscular or intravenous injection, distributing widely in tissues, particularly at infection sites. The drug, primarily eliminated unchanged via the kidneys, has a short half-life of 2-3 hours in those with normal renal function. However, renal impairment can prolong this duration. Individualized dosing and therapeutic drug monitoring are common, ensuring effective levels while minimizing toxicity risk. Gentamicin's post-antibiotic effect further contributes to its pharmacokinetic characteristics, emphasizing the need for regular monitoring of serum levels and renal function for safe and effective use. |
| Storage | Seal and store in a dry place. |
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